GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9487094 | 1 | rs12197114 | chr6:109735498 | SMPD2 | chr6:109761931-109765121:+ | 0.22 | 4.06 | 5.93E-5 | Height |
| BLCA | cis | rs1577917 | 1 | rs12199516 | chr6:86726221 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.37 | 6.58E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12199784 | chr6:86726808 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.4 | 5.22E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12200330 | chr6:86656653 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.46 | 3.14E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12201571 | chr6:86609750 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.45 | 3.38E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12201735 | chr6:86656939 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -8.95 | 1.55E-17 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12201741 | chr6:86602619 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -9.02 | 9.09E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12201880 | chr6:86627007 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -9.01 | 9.54E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs9473555 | 1 | rs12202075 | chr6:49427655 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.65 | 3.17E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs12202075 | chr6:49427655 | MUT | chr6:49398994-49431031:- | 0.28 | 5.51 | 6.48E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs1577917 | 1 | rs12203493 | chr6:86758642 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.25 | 1.64E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12203924 | chr6:86776412 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.25 | 1.64E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12204015 | chr6:86598334 | SNHG5 | chr6:86386726-86388451:- | -0.59 | -10.66 | 2.13E-23 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12204365 | chr6:86700532 | SNHG5 | chr6:86386726-86388451:- | -0.49 | -8.73 | 7.95E-17 | Response to antipsychotic treatment |
| BLCA | cis | rs9491140 | 1 | rs12204812 | chr6:124681503 | NKAIN2 | chr6:124125069-125146784:+ | 0.26 | 4.51 | 8.61E-6 | Neuroticism |